Premier League clubs have voted against allowing teams to make five substitutions per game.
However, the English top flight will apply to introduce concussion substitutes in the new year, after football's lawmakers IFAB agreed to trial the idea yesterday.
While the standard number of substitutions per game remains at three, clubs did vote to increase the number of subs on the bench from seven to nine.
However, the news will come as a blow to the likes of Jurgen Klopp.
The Liverpool manager has seen his squad ravaged by injuries, something he feels could have been alleviated by the allowance of five substitutions.
Speaking after they were held to a 1-1 draw at Brighton, Klopp said, "It’s about the players.
"Each moment when it would happen it would be good for the players.
Brighton lost today two players and they played one game a week with muscle injuries, so the most difficult time is coming up now."
His Manchester City counterpart Pep Guardiola had described the limit of three substitutions as "a disaster".
Five substitutions per game were permitted when the Premier League resumed in the summer, but they became the only major European League to rescind the increase when their 2020-21 season began.
A move from three to five substitutions had been voted down twice already before Thursday's shareholder meeting, and again failed to reach the 14-team threshold required for change.
Clubs have voted in favour of introducing concussion subs.
Up to two additional replacements will be allowed if a player is suspected of sustaining, or is diagnosed with, a concussion.
