Jack Conan will make his 100th appearance for Leinster in Friday's Guinness PRO14 game away to the Dragons.
Harry and Ross Byrne will start a Leinster game together for the first time, while Luke McGrath will captain the side.
Max O’Reilly starts at full-back with Cian Kelleher and Dave Kearney selected on the wings.
Ross Byrne will be partnered in the centre by the fit-again Rory O’Loughlin and McGrath is joined by Harry Byrne in the half-backs.
In the pack, Peter Dooley, James Tracy and Michael Bent are the front row selected by Leo Cullen.
Ross Molony and Ryan Baird form the second row pairing and it's a back row of Josh Murphy, Scott Penny and Conan, who will win his 100th cap for the Province almost seven years on from his debut.
20-year-old loosehead prop Marcus Hanan could make his debut off the bench should he be introduced.
Leinster team:
15. Max O’Reilly
14. Cian Kelleher
13. Rory O’Loughlin
12. Ross Byrne
11. Dave Kearney
10. Harry Byrne
9. Luke McGrath CAPTAIN
1. Peter Dooley
2. James Tracy
3. Michael Bent
4. Ross Molony
5. Ryan Baird
6. Josh Murphy
7. Scott Penny
8. Jack Conan
Replacements:
16. Dan Sheehan
17. Marcus Hanan
18. Tom Clarkson
19. Devin Toner
20. Scott Fardy
21. Rowan Osborne
22. David Hawkshaw
23. Jamie Osborne
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