The owner of Zara is to close up to 1,200 stores around the world.
Inditex says it will be shutting down outlets as there has been a 44 percent fall in sales.
The fashion retailer also owns brands such as Massimo Dutti, Bershka and Pull and Bear.
It's not clear yet if Irish stores will be affected.
It's the latest high street chain to be impacted by Covid-19 and follows the news that
Mothercare Ireland is closing all 14 of its stores with the loss of 197 jobs.
The retailer says it has ceased trading with immediate effect.
General Secretary of Mandate Trade Union John Douglas says the pandemic has been tough for some retailers:
"It's devastating for many of our members who would have worked all of their careers in retail. Unfortunately this pandemic has changed the face of retailing."
