About one in every 17 people in Belmullet local electoral area in Co Mayo had Covid-19 in the space of two weeks.
The region had by far the highest incidence rate in the country.
The data reflects on the 14-day incidence rates of confirmed cases of Covid-19 between December 29th and this Monday.
During that period, the country's rate was 1,410 per 100,000 people - meaning one in every 71 people had the virus.
Twenty areas of the country had rates of over 2,000 per 100,000 people.
Belmullet LEA in Co Mayo had a rate of 6,032 - over four times the national average.
There were 760 cases in this region in the two weeks - and with a population of 12,600, it means every 17 people had the virus.
Border regions remained bad and the second highest was Dundalk South LEA in Co Louth, at 3,783 - a rate of one in every 26 people.
Adare-Rathkeale LEA in Co Limerick had a rate of 3,118 - with one in every 32 people getting infected.